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              專職PI
              蘇鋒濤 副研究員
              副研究員,博士
              E-mail: sufengtao@126.com
               

                蘇鋒濤博士,2010年畢業于中國科學院近代物理研究所。2010-2015年在美國德州大學西南醫學中心放射腫瘤學系做博士后研究。2016年至今在復旦大學附屬腫瘤醫院腫瘤研究所工作。長期從事腫瘤發生及腫瘤放射生物學機制研究。在Cell Reports、Oncotarget、Radiation Oncology等刊物發表論文多篇。


              研究領域:

                1.DNA復制損傷和腫瘤發生的機制研究;
                2.DNA損傷和修復的分子機理研究;
                3.腫瘤放療標記物的篩選和相關機制研究;
                4.腫瘤微環境和腫瘤放療;
                5.重離子治癌機理研究。


              代表性論著:

              1. Fengtao Su#, Hirohiko Yajima, Shibani Mukherjee, Steven M Yannone, Benjamin P Chen, David J Chen, Aroumougame Asaithamby. Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway.Oncotarget, 2016 Jan 5; 7(1):46-65. 
              2. Jiayun Zhu, Fengtao Su, Shibani Mukherjee, Eiichiro Mori, Burong Hu, Aroumougame Asaithamby. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle, 2015; 14(12):1809-22.
              3. Fengtao Su#, Shibani Mukherjee, Yanyong Yang, Eiichiro Mori, Souparno Bhattacharya, Junya Kobayashi, Steven M. Yannone, David J. Chen, Aroumougame Asaithambyemail. Nonenzymatic Role for WRN in Preserving Nascent DNA Strands after Replication Stress. Cell Reports, 2014 Nov 20; 9(4):1387-401.
              4. Gerelchuluun A, Zhu Jiayun, Su Fengtao, Asaithamby A, Chen DJ, Tsuboi K. Homologous recombination pathway may play a major role in high-LET radiation-induced DNA double-strand break repair. J. Radiation Research, 3, 2014.
              5. Jufang Wang, Jinpeng He, Fengtao Su, Nan Ding, Wengtao Hu, Bin Yao, Wei Wang and Guangming Zhou. Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition. Cell Death and Disease, 2013 Jun 27; 4:e699.
              6. Jufang Wang, Fengtao Su, Lubomir B Smilenov, Libin Zhou, Wentao Hu, Nan Ding, and Guangming Zhou. Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity. Radiation Oncology, 2011 Aug 17; 6:96. 
              7. Fengtao Su#, Lubomir B Smilenov, Thomas Ludwig, Libin Zhou, Jiayun Zhu, Guangming Zhou and Eric J Hall. Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis. Radiation Oncology, 2010 Feb 22; 5:15.
              8. Feng-tao Su#, Qiang Li, Xiao-dong JIN. Biological Effects of H1299 Cells Exposed to 12C Ion Beam and X-rays. Nuclear Physics Review, 2008; 25 (1): 72-76.
               
              復旦大學腫瘤研究所 通訊地址: 東安路270號2號樓1312室 64175590-5312 Email:fuci2012@126.com
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